Article
Acetate-mediated growth inhibition in sterol 14alpha-demethylation-deficient cells of Candida albicans.
Antimicrobial agents and chemotherapy - 1 Jan 1999
Shimokawa O, Nakayama H
Abstract excerpt
Candida albicans is a fungus thought to be viable in the presence of a deficiency in sterol 14alpha-demethylation. We showed in a strain of this species that the deficiency, caused either by a mutation or by an azole antifungal agent, made the cells susceptible to growth inhibition by acetate inc...
Topics
- Acetates
- Azoles
- Candida albicans
- Chromatography, Thin Layer
- Colony Count, Microbial
- Cytochrome P-450 Enzyme System
- Hydrogen-Ion Concentration
- Mutation
- Oxidoreductases
- Sterol 14-Demethylase
- Sterols