Article
Deficient utilization of succinate in a sterol 14 alpha-demethylation mutant of Candida albicans.
Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology - 1 Jan 1991
Shimokawa O, Nakayama H
Abstract excerpt
Growth of a wild-type strain (KD14) started after a lag of approximately 15 h when glucose-grown cells of Candida albicans were incubated at 25 degrees C, with succinate as a sole energy/carbon source. No growth was observed, however, for a sterol 14 alpha-demethylation mutant (KD4900). During the lag period, the wild-type cells retained their respiratory activity, as measured with glucose as an added substrate,...
Topics
- Candida albicans
- Culture Media
- Mutation
- Oxygen Consumption
- Succinates
