Article
Influence of methylfenpropidine on growth, sterol content and fatty acid composition of Candida albicans.
Folia microbiologica - 1 Jan 2000
Sajbidor J, Breierová E, Lamacka M, Bohov P
Abstract excerpt
The effect of methylfenpropidine on growth, lipid contents, sterol and fatty acid composition was investigated in 5 strains of Candida albicans. The sensitivity of the strains decreased in the order: wild strains > erg+ ade nysR > ade nysR erg (defective delta (8-7)-isomerase) > ade nysR erg (defective delta 5-desaturase). The presence of the inhibitor influenced fecosterol isomerization, episterol...
Topics
- Candida albicans
- Dose-Response Relationship, Drug
- Ergosterol
- Fatty Acids
- Fungicides, Industrial
- Models, Chemical
- Molecular Structure
- Mutation
- Piperidines
- Sterols
