Host cell-dependent replication of HIV-1 gag MA, CA, and NC mutants are independent of the functions of Vif and Vpu.

doi:10.3892/ijmm.3.1.91

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Article

Host cell-dependent replication of HIV-1 gag MA, CA, and NC mutants are independent of the functions of Vif and Vpu.

International journal of molecular medicine - 1 Jan 1999

Shimano R, Inubushi R, Adachi A

Abstract excerpt

We have previously shown that some gag gene mutants of human immunodeficiency virus type 1 (HIV-1) display a replication-defect in a cell-dependent manner. We and others have also demonstrated that the requirement of vif and vpu genes for HIV-1 replication is cell-dependent. To determine whether...

Topics

Capsid
Capsid Proteins
Cell Line
Gene Products, gag
Gene Products, vif
HIV Antigens
HIV Core Protein p24
HIV-1
Human Immunodeficiency Virus Proteins
Humans
Mutation
Recombinant Fusion Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Tumor Cells, Cultured

Viral Proteins

Viral Regulatory and Accessory Proteins

Virus Replication

gag Gene Products, Human Immunodeficiency Virus

vif Gene Products, Human Immunodeficiency Virus

Source

Open in PubMed

Identifiers

PMID: 9864392
DOI: 10.3892/ijmm.3.1.91

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9864392-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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