Cell-dependent requirement of human immunodeficiency virus type 1 Vif protein for maturation of virus particles

Abstract excerpt

A highly sensitive single-round infection assay using a bacterial chloramphenicol acetyltransferase was developed to analyze an early stage of human immunodeficiency virus type 1 replication. By a combination of transfection and single-round infection assay, a virus with a vif mutation, depending on host cells from which the virus was derived, was demonstrated to be defective at the early phase of infection...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteriophages and microbial interactions
• Share to HIV/AIDS drug development and treatment
• Share to HIV Research and Treatment