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Article

[Function of human immunodeficiency virus type 1 nef gene product in virus replication].

[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 May 1996

Tokunaga K

Abstract excerpt

We comparatively analyzed the replication kinetics of wild-type (wt) and nef mutant human immunodeficiency virus type 1 (HIV-1) in several CD4-positive cell lines, in order to clarify the molecular function of Nef protein. The delayed growth of nef mutant virus was observed at the initial stage of replication in all cell lines examined. This phenomenon was greatly amplified in the absence of vpu gene. In order to...

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Share to CD4-Positive T-Lymphocytes
Share to Gene Products, env
Share to Gene Products, nef

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 8752529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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