Article
[Function of human immunodeficiency virus type 1 nef gene product in virus replication].
[Hokkaido igaku zasshi] The Hokkaido journal of medical science - 1 May 1996
Tokunaga K
Abstract excerpt
We comparatively analyzed the replication kinetics of wild-type (wt) and nef mutant human immunodeficiency virus type 1 (HIV-1) in several CD4-positive cell lines, in order to clarify the molecular function of Nef protein. The delayed growth of nef mutant virus was observed at the initial stage o...
Topics
- CD4-Positive T-Lymphocytes
- Gene Products, env
- Gene Products, nef
- Genes, nef
- HIV-1
- Humans
- Mutation
- Virion
- Virus Replication
- nef Gene Products, Human Immunodeficiency Virus
