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Article

Both virus and host components are important for the manifestation of a Nef- phenotype in HIV-1 and HIV-2.

Virology - 20 Oct 1995

Ryan-Graham M A, Peden K W

Abstract excerpt

While it has been demonstrated that the Nef protein of simian immunodeficiency virus is obligatory for the establishment of high viral loads and the development of simian AIDS in rhesus macaques, demonstrating a critical role for the human immunodeficiency virus (HIV) Nef protein in tissue cultur...

Topics

Amino Acid Sequence
Base Sequence
CD4-Positive T-Lymphocytes
Cell Line
Cells, Cultured
DNA, Viral
Frameshift Mutation
Gene Products, nef
Genes, nef
HIV-1
HIV-2
Humans
Kidney

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukocytes, Mononuclear

Molecular Sequence Data

Open Reading Frames

Phenotype

Transfection

Source

Identifiers

PMID: 7483259
DOI: 10.1006/viro.1995.1556

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7483259-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Both virus and host components are important for the manifestation of a Nef- phenotype in HIV-1 and HIV-2.PMID 7483259Read ↗

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Effect of nef alleles on replication of human immunodeficiency virus type 1.Semantic proximity Read ↗

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