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Article

Both virus and host components are important for the manifestation of a Nef- phenotype in HIV-1 and HIV-2.

Virology - 20 Oct 1995

Ryan-Graham M A, Peden K W

Abstract excerpt

While it has been demonstrated that the Nef protein of simian immunodeficiency virus is obligatory for the establishment of high viral loads and the development of simian AIDS in rhesus macaques, demonstrating a critical role for the human immunodeficiency virus (HIV) Nef protein in tissue culture has been elusive. Data have been contradictory as to whether Nef has a negative or positive influence on in vitro...

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Identifiers

PMID: 7483259
DOI: 10.1006/viro.1995.1556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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