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Article

Biochemical uncovering of mdm2/p53 complexes in liposarcomas parallels their immunohistochemical detection.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 1999

Butò S, Pierotti M A, Tamborini E, Della Torre G, Lavarino C, Rilke F, Pilotti S

Abstract excerpt

Recent observations indicate the existence of pathogenetically distinct groups of well-differentiated (WD) dedifferentiated (DD) liposarcomas. In the retroperitoneal WD-DD liposarcomas, the predominant phenotype is represented by the aberrant (overexpressed) mdm2+/p53+ wild-type profile. At the nonretroperitoneal site, the WD liposarcomas present a wider association of MDM2/P53 gene expression; i.e., mdm2+/p53+,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Proteins

Share to Polymorphism, Single-Stranded Conformational

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Share to Proto-Oncogene Proteins c-mdm2

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Source

Identifiers

PMID: 10565683
DOI: 10.1097/00019606-199909000-00004

Genes

MDM2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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