Article
rexB of bacteriophage lambda is an anti-cell death gene.
Proceedings of the National Academy of Sciences of the United States of America - 22 Dec 1998
Engelberg-Kulka H, Reches M, Narasimhan S, Schoulaker-Schwarz R, Klemes Y, Aizenman E, Glaser G
Abstract excerpt
In Escherichia coli, programmed cell death is mediated through "addiction modules" consisting of two genes; the product of one gene is long-lived and toxic, whereas the product of the other is short-lived and antagonizes the toxic effect. Here we show that the product of lambdarexB, one of the fe...
Topics
- Adenosine Triphosphatases
- Bacteriophage lambda
- Cloning, Molecular
- Endopeptidase Clp
- Escherichia coli
- Genotype
- Guanylyl Imidodiphosphate
- Ligases
- Lysogeny
- Mutagenesis, Insertional
- Plasmids
- Recombinant Proteins
- Serine Endopeptidases
- Viral Proteins