The Rex system of bacteriophage lambda: tolerance and altruistic cell death.

doi:10.1101/gad.6.3.497

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Article

The Rex system of bacteriophage lambda: tolerance and altruistic cell death.

Genes & development - 1 Mar 1992

Parma D H, Snyder M, Sobolevski S, Nawroz M, Brody E, Gold L

Abstract excerpt

The rexA and rexB genes of bacteriophage lambda encode a two-component system that aborts lytic growth of bacterial viruses. Rex exclusion is characterized by termination of macromolecular synthesis, loss of active transport, the hydrolysis of ATP, and cell death. By analogy to colicins E1 and K, these results can be explained by depolarization of the cytoplasmic membrane. We have fractionated cells to determine...

Topics

Adenosine Triphosphate
Alkaline Phosphatase
Amino Acid Sequence
Bacteriophage lambda
Base Sequence
Electrophoresis, Polyacrylamide Gel
Gene Expression
Genes, Viral
Genes, pX
Genetic Vectors
Hydrogen-Ion Concentration

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Hydrolysis

Ion Channels

Molecular Sequence Data

Mutation

Recombinant Fusion Proteins

Viral Proteins

Source

Open in PubMed

Identifiers

PMID: 1372278
DOI: 10.1101/gad.6.3.497

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1372278-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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