Article
Delayed-relaxed response explained by hyperactivation of RelE.
Molecular microbiology - 1 Jul 2004
Christensen Susanne K, Gerdes Kenn
Abstract excerpt
Escherichia coli encodes two rel loci, both of which contribute to the control of synthesis of macromolecules during amino acid starvation. The product of relA (ppGpp synthetase I) is responsible for the synthesis of guanosine tetraphosphate, ppGpp, the signal molecule that exerts stringent control of stable RNA synthesis. The second rel locus, relBE, was identified by mutations in relB that confer a so-called...
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