Article
Insulin-like growth factor-2 regulation of conceptus composition: effects of the trophectoderm and inner cell mass genotypes in the mouse.
Biology of reproduction - 1 Jan 1999
Gardner R L, Squire S, Zaina S, Hills S, Graham C F
Abstract excerpt
The purpose of this study was to measure the effect of insulin-like growth factor-2 deficiency on the growth of the mouse conceptus. Initial observations on normal development in the 129J/Sv strain established that wet and dry weights were reduced by 35% when the insulin-like growth factor-2 gene...
Topics
- Amnion
- Animals
- Blastocyst
- Body Fluids
- Chimera
- DNA
- Ectoderm
- Embryo, Mammalian
- Embryonic and Fetal Development
- Extracellular Space
- Female
- Genotype
- Gestational Age
- Insulin-Like Growth Factor II
- Male
- Mice
- Organ Size
- Placenta