Article
Influence of fetal and maternal genotype for circulating insulin-like growth factor I on fetal growth in mice.
Journal of reproduction and fertility - 1 May 1994
Morel P C, Blair H T, Ormsby J E, Breier B H, McCutcheon S N, Gluckman P D
Abstract excerpt
The role of insulin-like growth factor I in the regulation of fetal growth was investigated in two lines of mice selected for high or low concentrations of this factor in plasma. In Expt 1, females from each line were mated with males of the reciprocal line to generate fetuses of equivalent genotype. Females with low concentration of the factor in plasma exhibited the typical negative relationship between mean...
Topics
- Animals
- Embryo Transfer
- Embryonic and Fetal Development
- Female
- Fetal Blood
- Fetus
- Genotype
- Insulin-Like Growth Factor I
- Litter Size
- Mice
- Mice, Inbred Strains