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Placentomegaly in Cloned Mouse Concepti Caused by Expansion of the Spongiotrophoblast Layer1

1 Dec 2001

Abstract excerpt

Hypertrophic placenta, or placentomegaly, has been reported in cloned cattle and mouse concepti, although their placentation processes are quite different from each other. It is therefore tempting to assume that common mechanisms underlie the impact of somatic cell cloning on development of the trophoblast cell lineage that gives rise to the greater part of fetal placenta. To characterize the nature of...

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PMID: 11717146
DOI: 10.1095/biolreprod65.6.1813

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