Article
Lack of association between the hSKCa3 channel gene CAG polymorphism and schizophrenia.
American journal of medical genetics - 16 Apr 1999
Joober R, Benkelfat C, Brisebois K, Toulouse A, Lafrenière R G, Turecki G, Lal S, Bloom D, Labelle A, Lalonde P, Fortin D, Alda M, Palmour R, Rouleau G A
Abstract excerpt
Genetic anticipation, a phenomenon characterized by increased severity of symptoms and earlier age at onset of a disease in successive generations, is believed to be present in schizophrenia. In several neurodegenerative diseases showing anticipation, the mutation causing the disease is an expanded trinucleotide repeat. Therefore, genes containing trinucleotide repeats prone to expansion have become a suitable...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.