Article
Association analysis of CAG repeats at the KCNN3 locus in Indian patients with bipolar disorder and schizophrenia.
American journal of medical genetics - 4 Dec 2000
Saleem Q, Sreevidya V S, Sudhir J, Savithri J V, Gowda Y, B-Rao C, Benegal V, Majumder P P, Anand A, Brahmachari S K, Jain S
Abstract excerpt
Bipolar affective disorder and schizophrenia are severe behavioral disorders with a lifetime risk of approximately 1% in the population worldwide. There is evidence that these diseases may manifest the phenomenon of anticipation similar to that seen in diseases caused by trinucleotide repeat expansions. A recent report has implicated a potassium channel-coding gene, KCNN3, which contains a polymorphic CAG repeat...
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