Article
The human small conductance calcium-regulated potassium channel gene (hSKCa3) contains two CAG repeats in exon 1, is on chromosome 1q21.3, and shows a possible association with schizophrenia.
Neurogenetics - 1 Aug 1998
Wittekindt O, Jauch A, Burgert E, Schärer L, Holtgreve-Grez H, Yvert G, Imbert G, Zimmer J, Hoehe M R, Macher J P, Chiaroni P, van Calker D, Crocq M A, Morris-Rosendahl D J
Abstract excerpt
Mutations in various ion channel genes are responsible for neuromuscular and other neurological disorders. We have previously identified the human small conductance calcium-activated potassium channel gene (hSKCa3) which has two tandemly arranged CAG repeats in its 5' region. Here we have isolated the first genomic clones containing the gene and have shown that both repeats are in exon 1. Homology to the...
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