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Article

Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder?

Molecular psychiatry - 1 Jan 1998

Chandy K G, Fantino E, Wittekindt O, Kalman K, Tong L L, Ho T H, Gutman G A, Crocq M A, Ganguli R, Nimgaonkar V, Morris-Rosendahl D J, Gargus J J

Abstract excerpt

Many human hereditary neurodegenerative diseases are caused by expanded CAG repeats, and anonymous CAG expansions have also been described in schizophrenia and bipolar disorder. We have isolated and sequenced a novel human cDNA encoding a neuronal, small conductance calcium-activated potassium channel (hSKCa3) that contains two arrays of CAG trinucleotide repeats. The second CAG repeat in hSKCa3 is highly...

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PMID: 9491810
DOI: 10.1038/sj.mp.4000353

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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Isolation of a novel potassium channel gene hSKCa3 containing a polymorphic CAG repeat: a candidate for schizophrenia and bipolar disorder?PMID 9491810Read ↗

The human small conductance calcium-regulated potassium channel gene (hSKCa3) contains two CAG repeats in exon 1, is on chromosome 1q21.3, and shows a possible association with schizophrenia.Semantic proximity Read ↗

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Mapping of hKCa3 to chromosome 1q21 and investigation of linkage of CAG repeat polymorphism to schizophrenia.Semantic proximity Read ↗

hSKCa3: a candidate gene for schizophrenia?Semantic proximity Read ↗

Schizophrenia and polymorphic CAG repeats array of calcium-activated potassium channel (KCNN3) gene in Serbian population.Semantic proximity Read ↗

Further support for an association between a polymorphic CAG repeat in the hKCa3 gene and schizophrenia.Semantic proximity Read ↗

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Genetic association study of a polymorphic CAG repeats array of calcium-activated potassium channel (KCNN3) gene and schizophrenia among the Chinese population from Taiwan.Semantic proximity Read ↗

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