Cystic fibrosis and the phenotypic expression of autosomal dominant polycystic kidney disease.

doi:10.1016/s0272-6386(98)70072-1

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Cystic fibrosis and the phenotypic expression of autosomal dominant polycystic kidney disease.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Dec 1998

O'Sullivan D A, Torres V E, Gabow P A, Thibodeau S N, King B F, Bergstralh E J

Abstract excerpt

Recent experiments in cultured cyst epithelial cells from kidneys of patients with autosomal dominant polycystic kidney disease (ADPKD) have shown that the cystic fibrosis (CF) transmembrane conductance regulator (CFTR) is present in the apical surface of these cells and mediates chloride (Cl-) a...

Topics

Adult
Aged
Creatinine
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
DNA Mutational Analysis
Female
Genotype
Humans
Kidney
Magnetic Resonance Imaging
Male
Middle Aged
Pedigree
Phenotype
Polycystic Kidney, Autosomal Dominant
Tomography, X-Ray Computed

Source

Open in PubMed

Identifiers

PMID: 9856513
DOI: 10.1016/s0272-6386(98)70072-1

Genes

CFTR
PKD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9856513-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics