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Article

Estrogen treatment enhances hereditary renal tumor development in Eker rats.

Carcinogenesis - 1 Nov 1998

Wolf D C, Goldsworthy T L, Donner E M, Harden R, Fitzpatrick B, Everitt J I

Abstract excerpt

Hormonal influences are known to affect the development of renal cell carcinoma in man and laboratory animal models. We tested the hypothesis that estrogen treatment or ovariectomy of rats modulates renal tumor development using tuberous sclerosis 2 (Tsc2) heterozygous mutant (Eker) rats in which...

Topics

Animals
Carcinoma, Renal Cell
Estrogens
Female
Kidney Neoplasms
Mutation
Precancerous Conditions
Rats
Repressor Proteins
Tuberous Sclerosis Complex 2 Protein
Tumor Suppressor Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9855022
DOI: 10.1093/carcin/19.11.2043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9855022-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Estrogen treatment enhances hereditary renal tumor development in Eker rats.PMID 9855022Read ↗

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The Genetic Basis of Kidney Cancer: Why is Tuberous Sclerosis Complex Often Overlooked?Semantic proximity Read ↗

Carcinogen-Specific Gene Expression Profiles in Short-term Treated Eker and Wild-type Rats Indicative of Pathways Involved in Renal TumorigenesisSemantic proximity Read ↗

Molecular genetic basis of renal carcinogenesis in the Eker rat model of tuberous sclerosis (Tsc2).Semantic proximity Read ↗

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