Article
Impaired growth and differentiation of diploid but not immortal melanoblasts from endothelin receptor B mutant (piebald) mice.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 1998
Sviderskaya E V, Easty D J, Bennett D C
Abstract excerpt
Endothelin 3 (Edn3) and its preferred receptor, endothelin receptor B (Ednrb), are implicated in development, especially that of two neural-crest-derived cell lineages: melanocytes and enteric ganglion cells. Mice and humans with a null mutation at either locus can show major deficiencies in both...
Topics
- Animals
- Biomarkers
- Blotting, Northern
- Cell Differentiation
- Cell Division
- Cells, Cultured
- Endothelin-3
- Intramolecular Oxidoreductases
- Melanocytes
- Membrane Glycoproteins
- Mice
- Mice, Inbred C57BL
