Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dct::lacZ ES cells: a novel cellular model to study melanocyte determination and differentiation.

Pigment cell research - 1 Apr 2004

Pla Patrick, Solov'eva Olga, Moore Robert, Alberti Christophe, Kunisada Takahiro, Larue Lionel

Abstract excerpt

Embryonic stem (ES) cells differentiate into various cell lineages in vitro. A procedure was previously designed to promote the differentiation of ES cells towards the melanocyte lineage and to obtain large and reproducible amounts of melanocytes. To elucidate the main events that lead to the development of melanocytes in vitro, we used transgenic Dct::lacZ mouse blastocysts to establish ES cell lines expressing...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Division
Share to Cell Lineage
Share to Cell Movement

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chick Embryo

Share to Embryo, Mammalian

Share to Fibroblast Growth Factor 2

Share to Melanocytes

Share to Stem Cells

Source

Identifiers

PMID: 15016303
DOI: 10.1046/j.1600-0749.2003.00121.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dct::lacZ ES cells: a novel cellular model to study melanocyte determination and differentiation.PMID 15016303Read ↗

Key discoveries in melanocyte development.Semantic proximity Read ↗

De- and re-differentiation of the melanocytic lineage.Semantic proximity Read ↗

Cooperative and indispensable roles of endothelin 3 and KIT signalings in melanocyte development.Semantic proximity Read ↗

Differential contribution of direct-developing and stem cell-derived melanocytes to the zebrafish larval pigment pattern.Semantic proximity Read ↗

Establishment by an original single-cell cloning method and characterization of an immortal mouse melanoblast cell line (NCCmelb4).Semantic proximity Read ↗

Generation of Pmel-dependent conditional and inducible Cre-driver mouse line for melanocytic-targeted gene manipulation.Semantic proximity Read ↗

Activation of the receptor tyrosine kinase Kit is required for the proliferation of melanoblasts in the mouse embryo.Semantic proximity Read ↗

The roles of Frizzled-3 and Wnt3a on melanocyte development: in vitro studies on neural crest cells and melanocyte precursor cell lines.Semantic proximity Read ↗

Melanocyte development in vivo and in neural crest cell cultures: crucial dependence on the Mitf basic-helix-loop-helix-zipper transcription factor.Semantic proximity Read ↗

Two distinct types of mouse melanocyte: differential signaling requirement for the maintenance of non-cutaneous and dermal versus epidermal melanocytes.Semantic proximity Read ↗

Insights into Differentiation of Melanocytes from Human Stem Cells and Their Relevance for Melanoma TreatmentSemantic proximity Read ↗

Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.