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Article

A highly polymorphic CA repeat marker at the human tumor necrosis factor alpha (TNFA alpha) locus.

Journal of human genetics - 1 Jan 1998

Tsukamoto K, Ohta N, Shirai Y, Emi M

Abstract excerpt

Tumor necrosis factor alpha (TNF alpha) in activated monocytes exerts cytotoxic activity and has a variety of other biological effects. We isolated a polymorphic dinucleotide (CA) repeat sequence from a genomic clone containing the gene located at 6p21.3. High heterozygosity (0.80) makes this polymorphism a useful marker in the genetic study of disorders affecting immunological response and cell differentiation.

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Source

Identifiers

PMID: 9852684
DOI: 10.1007/s100380050090

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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