Article
A polymorphic microsatellite marker in the human p55 TNF receptor, CD120a.
Genes and immunity - 1 Feb 2000
Eskdale J, Turestkaya R L, Armstrong C, Kuprash D V, Nedospasov S A, Gallagher G
Abstract excerpt
We provide characterization of a highly polymorphic dinucleotide repeat in the human TNF-receptor 1 gene (TNFR1, TNFRp55, CD120a). We have observed 11 alleles at this locus in individuals from the West of Scotland. In a panel of healthy, unrelated individuals from the West of Scotland (n = 143), the overall heterozygosity was 68%, indicating the potential usefulness of these markers in immunogenetic studies.
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