DNA mismatch repair genes and their association with colorectal cancer (Review).

doi:10.3892/ijmm.1.2.469

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Article

DNA mismatch repair genes and their association with colorectal cancer (Review).

International journal of molecular medicine - 1 Feb 1998

Whitehouse A, Meredith D M, Markham A F

Abstract excerpt

Mismatch repair genes are involved in increasing the fidelity of replication by specific repair of DNA polymerase incorporation errors. In Escherichia coli, the best studied mismatch repair (MMR) pathway is the methyl-directed long patch repair system which is mediated by three gene products; Mut...

Topics

Colorectal Neoplasms, Hereditary Nonpolyposis
DNA Repair
DNA-Binding Proteins
Genetic Predisposition to Disease
Humans
Multidrug Resistance-Associated Proteins
MutS Homolog 3 Protein
Mutation

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