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Article

DNA repair and colorectal cancer.

Gastroenterology clinics of North America - 1 Dec 1996

Marra G, Boland C R

Abstract excerpt

The mismatch repair system plays a major role in the processing of recombination intermediates and in the repair of errors made during DNA replication or resulting from chemical damage to DNA. Human homologues of the bacterial and yeast mismatch repair genes have been recently identified, and mutations in these genes have been found to show risk for tumor development in hereditary nonpolyposis colorectal cancer...

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PMID: 8960891
DOI: 10.1016/s0889-8553(05)70273-9

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