Article
CRK9 contributes to regulation of mitosis and cytokinesis in the procyclic form of Trypanosoma brucei.
BMC cell biology - 21 Sept 2009
Gourguechon Stephane, Wang Ching C
Abstract excerpt
BACKGROUND: The Trypanosoma brucei cell cycle is regulated by combinations of cyclin/CRKs (cdc2 related kinases). Recently, two additional cyclins (CYC10, CYC11) and six new CRK (CRK7-12) homologues were identified in the T. brucei genome database 12. RESULTS: Individual RNAi knockdowns of these new proteins in the procyclic form of T. brucei showed no apparent phenotype except for the CRK9 depletion, which...
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