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Article

Isolation of Trypanosoma brucei CYC2 and CYC3 cyclin genes by rescue of a yeast G(1) cyclin mutant. Functional characterization of CYC2.

The Journal of biological chemistry - 24 Mar 2000

Van Hellemond J J, Neuville P, Schwarz R T, Matthews K R, Mottram J C

Abstract excerpt

Two Trypanosoma brucei cyclin genes, CYC2 and CYC3, have been isolated by rescue of the Saccharomyces cerevisiae mutant DL1, which is deficient in CLN G(1) cyclin function. CYC2 encodes a 24-kDa protein that has sequence identity to the Neurospora crassa PREG1 and the S. cerevisiae PHO80 cyclin. CYC3 has the most sequence identity to mitotic B-type cyclins from a variety of organisms. Both CYC2 and CYC3 are...

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Source

Identifiers

PMID: 10722661
DOI: 10.1074/jbc.275.12.8315

Genes

CRK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Isolation of Trypanosoma brucei CYC2 and CYC3 cyclin genes by rescue of a yeast G(1) cyclin mutant. Functional characterization of CYC2.PMID 10722661Read ↗

Isolation of a mitotic-like cyclin homologue from the protozoan Trypanosoma brucei.Semantic proximity Read ↗

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