Transforming growth factor-beta1 resistance in a thyroid cancer model of tumor necrosis factor-alpha resistance.

doi:10.1089/thy.1998.8.1065

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Article

Transforming growth factor-beta1 resistance in a thyroid cancer model of tumor necrosis factor-alpha resistance.

Thyroid : official journal of the American Thyroid Association - 1 Nov 1998

Pang X P, Hershman J M

Abstract excerpt

We have shown that both tumor necrosis factor-alpha (TNF-alpha) and transforming growth factor-beta1 (TGF-beta1) inhibit the growth of the human papillary thyroid carcinoma (PTC) cell line, NPA. In previous work, we developed NPA cells that were resistant to the growth suppressive effect of TNF-a...

Topics

Cell Division
Cell Line
Drug Resistance
Enzyme-Linked Immunosorbent Assay
Humans
Mutation
Proto-Oncogene Proteins c-fos
Recombinant Proteins
Thyroid Neoplasms
Transforming Growth Factor beta
Tumor Cells, Cultured
Tumor Necrosis Factor-alpha
Tumor Suppressor Protein p53

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Open in PubMed

Identifiers

PMID: 9848725
DOI: 10.1089/thy.1998.8.1065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9848725-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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