Effect of gene transfer of tumor necrosis factor receptors into human lung carcinoma cell line.

doi:10.1111/j.1349-7006.1998.tb03302.x

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Article

Effect of gene transfer of tumor necrosis factor receptors into human lung carcinoma cell line.

Japanese journal of cancer research : Gann - 1 May 1998

Ohara H, Hasegawa Y, Kawabe T, Ichiyama S, Hara T, Shimono Y, Saito H, Shimokata K

Abstract excerpt

The human lung adenocarcinoma cell line A549 is known to be resistant to tumor necrosis factor alpha (TNF-alpha)-mediated tumor cell lysis in spite of the expression of 55 kDa TNF receptor (TNF-R55) mRNA and its cell surface protein. In this study, we investigated the mechanism of TNF-alpha resis...

Topics

Adenocarcinoma
Cell Death
Humans
Lung Neoplasms
Mutation
Receptors, Tumor Necrosis Factor
Transfection
Tumor Cells, Cultured
Tumor Necrosis Factor-alpha

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