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Article

Effect of gene transfer of tumor necrosis factor receptors into human lung carcinoma cell line.

Japanese journal of cancer research : Gann - 1 May 1998

Ohara H, Hasegawa Y, Kawabe T, Ichiyama S, Hara T, Shimono Y, Saito H, Shimokata K

Abstract excerpt

The human lung adenocarcinoma cell line A549 is known to be resistant to tumor necrosis factor alpha (TNF-alpha)-mediated tumor cell lysis in spite of the expression of 55 kDa TNF receptor (TNF-R55) mRNA and its cell surface protein. In this study, we investigated the mechanism of TNF-alpha resistance and the role of two types of TNF receptors (TNF-R55 and TNF-R75 (75 kDa TNF receptor)). TNF-R55 or TNF-R75 cDNA...

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Source

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Identifiers

PMID: 9685865
DOI: 10.1111/j.1349-7006.1998.tb03302.x
PMCID: PMC5921841

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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