Article
Interferon-gamma gene microsatellite polymorphisms in patients with Graves' disease.
Thyroid : official journal of the American Thyroid Association - 1 Nov 1998
Siegmund T, Usadel K H, Donner H, Braun J, Walfish P G, Badenhoop K
Abstract excerpt
Although some of the susceptibility to Graves' disease is conferred by genes in the human leucocyte antigen (HLA) region on the short arm of chromosome 6, other genetic factors must also predispose. Among the cytokines involved in thyroid autoimmunity interferon-gamma (IFN-gamma) plays a key role...
Topics
- Alleles
- Gene Frequency
- Graves Disease
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- Humans
- Interferon-gamma
- Microsatellite Repeats
- Polymorphism, Genetic
- Reference Values