Article
Proto-oncogene PML controls genes devoted to MHC class I antigen presentation.
Nature - 26 Nov 1998
Zheng P, Guo Y, Niu Q, Levy D E, Dyck J A, Lu S, Sheiman L A, Liu Y
Abstract excerpt
Fragments of foreign antigens associated with class I molecules of the major histocompatibility complex (MHC) are presented at the cell surface to elicit an immune response. This presentation requires the coordinated expression of several genes contained in the MHC, including those encoding the M...
Topics
- 3T3 Cells
- Amino Acid Sequence
- Animals
- Antigen Presentation
- Cloning, Molecular
- DNA, Complementary
- Genes, Regulator
- Histocompatibility Antigens Class I
- Mice
- Molecular Sequence Data
- Mutation
- Neoplasm Proteins
- Nuclear Proteins
- Promyelocytic Leukemia Protein
- Protein Isoforms
- Proto-Oncogenes
- Reverse Transcriptase Polymerase Chain Reaction
- Transcription Factors