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Article

Human Cytomegalovirus Protein pp71 Disrupts Major Histocompatibility Complex Class I Cell Surface Expression

26 Dec 2005

Abstract excerpt

The human cytomegalovirus tegument protein pp71 is the product of the UL82 gene. Roles for pp71 in stimulating gene transcription, increasing infectivity of viral DNA, and the degradation of retinoblastoma family proteins have been described. Here we report a novel function for pp71 in limiting accumulation of cell surface major histocompatibility complex (MHC) class I complexes. MHC molecules were analyzed in...

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Identifiers

PMID: 16378997
DOI: 10.1128/jvi.80.2.951-963.2006

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Human Cytomegalovirus Protein pp71 Disrupts Major Histocompatibility Complex Class I Cell Surface ExpressionPMID 16378997Read ↗

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