Article
Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways.
Molecular biology of the cell - 1 Dec 1998
Tu Y, Li F, Wu C
Abstract excerpt
Many of the protein-protein interactions that are essential for eukaryotic intracellular signal transduction are mediated by protein binding modules including SH2, SH3, and LIM domains. Nck is a SH3- and SH2-containing adaptor protein implicated in coordinating various signaling pathways, includi...
Topics
- 3T3 Cells
- Adaptor Proteins, Signal Transducing
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Base Sequence
- Carrier Proteins
- Cell Line
- Cloning, Molecular
- DNA Primers
- DNA, Complementary
- DNA-Binding Proteins
- ErbB Receptors
- Gene Expression
- Humans