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Article

The Lnk adaptor protein: a key regulator of normal and pathological hematopoiesis.

Archivum immunologiae et therapiae experimentalis - 1 Dec 2012

Velazquez Laura

Abstract excerpt

The development and function of blood cells are regulated by specific growth factors/cytokines and their receptors' signaling pathways. In this way, these factors influence cell survival, proliferation and differentiation of hematopoietic cells. Central to this positive and/or negative control are the adaptor proteins. Since their identification 10 years ago, members of the Lnk adaptor protein family have proved...

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Identifiers

PMID: 22990499
DOI: 10.1007/s00005-012-0194-x

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