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Article

Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli.

Proceedings of the National Academy of Sciences of the United States of America - 27 Jun 2006

Galisteo Maria L, Yang Yan, Ureña Jesus, Schlessinger Joseph

Abstract excerpt

Ack/Ack1 is a nonreceptor protein tyrosine kinase that comprises a tyrosine kinase core, an SH3 domain, a Cdc42-binding region, a Ralt homology region, and a proline-rich region. Here we describe a detailed characterization of the Ack protein as well as the chromosomal localization of human Ack (chromosome 3q29) and the primary structure of murine Ack. We demonstrate that Ack is ubiquitously expressed, with...

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Identifiers

PMID: 16777958
DOI: 10.1073/pnas.0603714103
PMCID: PMC1502533

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EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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