Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli.

Proceedings of the National Academy of Sciences of the United States of America - 27 Jun 2006

Galisteo Maria L, Yang Yan, Ureña Jesus, Schlessinger Joseph

Abstract excerpt

Ack/Ack1 is a nonreceptor protein tyrosine kinase that comprises a tyrosine kinase core, an SH3 domain, a Cdc42-binding region, a Ralt homology region, and a proline-rich region. Here we describe a detailed characterization of the Ack protein as well as the chromosomal localization of human Ack (...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Spleen
Share to Thymus Gland
Share to Chromosomes, Human, Pair 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epidermal Growth Factor

Share to Fibronectins

Share to Oncogene Proteins

Share to Physical Chromosome Mapping

Share to Platelet-Derived Growth Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 16777958
DOI: 10.1073/pnas.0603714103
PMCID: PMC1502533

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16777958-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli.PMID 16777958Read ↗

Molecular and immunohistochemical analysis of signaling adaptor protein Crk in human cancersSemantic proximity Read ↗

Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.Semantic proximity Read ↗

Models of Crk Adaptor Proteins in CancerSemantic proximity Read ↗

ACK1/TNK2 kinase: molecular mechanisms and emerging cancer therapeuticsSemantic proximity Read ↗

Drosophila activated Cdc42 kinase has an anti-apoptotic function.Semantic proximity Read ↗

The N-terminal region of the atypical chemokine receptor ACKR2 is a key determinant of ligand binding.Semantic proximity Read ↗

Cripto-1 Activates Nodal- and ALK4-Dependent and -Independent Signaling Pathways in Mammary Epithelial CellsSemantic proximity Read ↗

CrkIII: a novel and biologically distinct member of the Crk family of adaptor proteinsSemantic proximity Read ↗

Integrin-linked kinase – essential roles in physiology and cancer biologySemantic proximity Read ↗

Somatic mutation in the ACK1 ubiquitin association domain enhances oncogenic signaling through EGFR regulation in renal cancer derived cells.Semantic proximity Read ↗

The Role of Shcbp1 in Signaling and DiseaseSemantic proximity Read ↗

Nck-2, a novel Src homology2/3-containing adaptor protein that interacts with the LIM-only protein PINCH and components of growth factor receptor kinase-signaling pathways.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.