Article
Induction of resistance to azole drugs in Trypanosoma cruzi.
Antimicrobial agents and chemotherapy - 1 Dec 1998
Buckner F S, Wilson A J, White T C, Van Voorhis W C
Abstract excerpt
Trypanosoma cruzi is the protozoan parasite that causes Chagas' disease, a frequently fatal illness affecting the heart and gastrointestinal systems. An estimated 16 million to 18 million people in Latin America and 50,000 to 100,000 people in the United States are infected with this pathogen. Treatment options for T. cruzi infections are suboptimal due to the toxicities and limited effectiveness of the available...
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