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Article

Characterisation of cloned lines of Trypanosoma brucei expressing stable resistance to MelCy and suramin.

Acta tropica - 1 Feb 1996

Scott A G, Tait A, Turner C M

Abstract excerpt

Two cloned drug-sensitive stocks of Trypanosoma brucei (STIB 247 and STIB 386) were each used to generate cloned lines expressing resistance to the melaminophenyl arsenical drug cymelarsan (247MelCyR and 386MelCyR) and to suramin (247SurR and 386SurR). The drug-resistance phenotypes were stable after passaging in mice in the absence of drug pressure and three of the lines were transmitted through tsetse flies...

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Identifiers

PMID: 8659324
DOI: 10.1016/0001-706x(96)00131-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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