Article
Correlation between triazole treatment history and susceptibility in clinically isolated Aspergillus fumigatus.
Antimicrobial agents and chemotherapy - 1 Sept 2012
Tashiro Masato, Izumikawa Koichi, Hirano Katsuji, Ide Shotaro, Mihara Tomo, Hosogaya Naoki, Takazono Takahiro, Morinaga Yoshitomo, Nakamura Shigeki, Kurihara Shintaro, Imamura Yoshifumi, Miyazaki Taiga, Nishino Tomoya, Tsukamoto Misuzu, Kakeya Hiroshi, Yamamoto Yoshihiro, Yanagihara Katsunori, Yasuoka Akira, Tashiro Takayoshi, Kohno Shigeru
Abstract excerpt
This is the first report of a detailed relationship between triazole treatment history and triazole MICs for 154 Aspergillus fumigatus clinical isolates. The duration of itraconazole dosage increased as the itraconazole MIC increased, and a positive correlation was observed (r = 0.5700, P < 0.0001). The number of itraconazole-naïve isolates dramatically decreased as the itraconazole MIC increased, particularly...
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