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Article

Involvement of IGF2 and H19 imprinting in choriocarcinoma development.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics - 1 Apr 1998

Wake N, Arima T, Matsuda T

Abstract excerpt

Complete hydatidiform mole is an abnormal pregnancy characterized by grossly swollen villi in the absence of a fetus (Kajii and Ohama 1997, Wake et al., 1978, Jacobs et al., 1980). It is well known that this abnormal pregnancy product is androgenetic in origin. The entire genome of the molar conceptus is paternally derived. The majority of moles result from fertilization of an empty egg by haploid sperm. The...

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Identifiers

PMID: 9833609

Genes

IGF2

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Related research

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Involvement of IGF2 and H19 imprinting in choriocarcinoma development.PMID 9833609Read ↗

Association of IGF2 and H19 imprinting with choriocarcinoma developmentSemantic proximity Read ↗

Parental imprinting of the human H19 geneSemantic proximity Read ↗

Igf2-H19, an imprinted tandem gene, is an important regulator of embryonic development, a guardian of proliferation of adult pluripotent stem cells, a regulator of longevity, and a ‘passkey’ to cancerogenesisSemantic proximity Read ↗

Imprinted H19 gene expression in embryogenesis and human cancer: the oncofetal connection.Semantic proximity Read ↗

Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes.Semantic proximity Read ↗

Paternal Hemizygosity in 11p15 in Mole-like Conceptuses: Two Case Reports.Semantic proximity Read ↗

Epigenetic regulation of the <i>Igf2/H19</i> gene clusterSemantic proximity Read ↗

Dissociation of IGF2 and H19 imprinting in human brain.Semantic proximity Read ↗

[Cytogenomic studies of hydatiform moles and gestational choriocarcinoma].Semantic proximity Read ↗

Familial hydatidiform molar pregnancy: the germline imprinting defect hypothesis?Semantic proximity Read ↗

More than insulator: multiple roles of CTCF at the H19-Igf2 imprinted domainSemantic proximity Read ↗

Biparental hydatidiform moles: a maternal effect mutation affecting imprinting in the offspring.Semantic proximity Read ↗

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