Article
Familial hydatidiform molar pregnancy: the germline imprinting defect hypothesis?
Current topics in microbiology and immunology - 1 Jan 2006
El-Maarri O, Slim R
Abstract excerpt
Imprinting is the uniparental expression of a set of genes. Somatic cells carry two haploid sets of chromosomes, one maternal and one paternal, while germ cells contain only one of the two forms of chromosomes, male or female. This implies that during early embryogenesis the cells committed for developing the future germ cell lineage, the primordial germ cells, which are diploid, have to undergo a total...
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