Article
Role of SarA in virulence determinant production and environmental signal transduction in Staphylococcus aureus.
Journal of bacteriology - 1 Dec 1998
Chan P F, Foster S J
Abstract excerpt
The staphylococcal accessory regulator (encoded by sarA) is an important global regulator of virulence factor biosynthesis in Staphylococcus aureus. To further characterize its role in virulence determinant production, an sarA knockout mutant was created by insertion of a kanamycin antibiotic resistance cassette into the sarA gene. N-terminal sequencing of exoproteins down-regulated by sarA identified several...
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