Article
Role of SarA in virulence determinant production and environmental signal transduction in Staphylococcus aureus.
Journal of bacteriology - 1 Dec 1998
Chan P F, Foster S J
Abstract excerpt
The staphylococcal accessory regulator (encoded by sarA) is an important global regulator of virulence factor biosynthesis in Staphylococcus aureus. To further characterize its role in virulence determinant production, an sarA knockout mutant was created by insertion of a kanamycin antibiotic res...
Topics
- Aerobiosis
- Anaerobiosis
- Bacterial Proteins
- Bacterial Toxins
- Base Sequence
- DNA Primers
- DNA, Bacterial
- Endopeptidases
- Enterotoxins
- Environment
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Hemolysin Proteins
- Humans
- Kinetics
- Mutagenesis, Insertional
- Phenotype
- Sequence Homology, Nucleic Acid