Article
sarU, a sarA homolog, is repressed by SarT and regulates virulence genes in Staphylococcus aureus.
Infection and immunity - 1 Jan 2003
Manna Adhar C, Cheung Ambrose L
Abstract excerpt
In searching the Staphylococcus aureus genome, we previously identified sarT, a homolog of sarA, which encodes a repressor for alpha-hemolysin synthesis. Adjacent but transcribed divergently to sarT is sarU, which encodes a 247-residue polypeptide, almost twice the length of SarA. Sequence alignment disclosed that SarU, like SarS, which is another SarA homolog, could be envisioned as a molecule with two halves,...
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