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Article

Staphylococcus aureus svrA: a gene required for virulence and expression of the agr locus.

Microbiology (Reading, England) - 1 Oct 2002

Garvis Steve, Mei Ji-Min, Ruiz-Albert Javier, Holden David W

Abstract excerpt

A Staphylococcus aureus gene originally identified by signature-tagged mutagenesis as being required for virulence was cloned, sequenced and named svrA. Hydropathy profiles revealed that SvrA is likely to be membrane associated, having two regions with six membrane-spanning domains, the regions separated by an extended hydrophilic loop. When compared with the wild-type strain, an svrA mutant expressed greatly...

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Share to Cloning, Molecular
Share to Gene Expression Regulation, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12368457
DOI: 10.1099/00221287-148-10-3235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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