SarZ Promotes the Expression of Virulence Factors and Represses Biofilm Formation by Modulating SarA and <i>agr</i> in <i>Staphylococcus aureus</i>

Abstract excerpt

Staphylococcus aureus is a remarkably adaptable organism capable of multiple modes of growth in the human host, as a part of the normal flora, as a pathogen, or as a biofilm. Many of the regulatory pathways governing these modes of growth are centered on the activities of two regulatory molecules, the DNA binding protein SarA and the regulatory RNAIII effector molecule of the agr system. Here, we describe the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antimicrobial Resistance in Staphylococcus
• Share to Bacterial biofilms and quorum sensing
• Share to Bacterial Genetics and Biotechnology