Article
saeRS and sarA act synergistically to repress protease production and promote biofilm formation in Staphylococcus aureus.
PloS one - 1 Jan 2012
Mrak Lara N, Zielinska Agnieszka K, Beenken Karen E, Mrak Ian N, Atwood Danielle N, Griffin Linda M, Lee Chia Y, Smeltzer Mark S
Abstract excerpt
Mutation of the staphylococcal accessory regulator (sarA) limits biofilm formation in diverse strains of Staphylococcus aureus, but there are exceptions. One of these is the commonly studied strain Newman. This strain has two defects of potential relevance, the first being mutations that preclude anchoring of the fibronectin-binding proteins FnbA and FnbB to the cell wall, and the second being a point mutation in...
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