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The role of environmental factors in the regulation of virulence-determinant expression in Staphylococcus aureus 8325-4

1 Sept 1998

Abstract excerpt

Staphylococcus aureus is a major human pathogen, which produces a variety of virulence determinants. To study environmental regulation of virulence-determinant production, several transcriptional reporter gene fusions were constructed. Chromosomal fusions were made with the staphylococcal accessory regulator (sarA), alpha-haemolysin (hla), surface protein A (spa) and toxic-shock syndrome toxin-1 (tst) genes. The...

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PMID: 9782494
DOI: 10.1099/00221287-144-9-2469

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