Article
Cryptic deletions and inversions of chromosome 21 in a phenotypically normal infant with transient abnormal myelopoiesis: a molecular cytogenetic study.
British journal of haematology - 1 Nov 1998
Kempski H M, Craze J L, Chessells J M, Reeves B R
Abstract excerpt
A case of transient abnormal myelopoiesis in a normal newborn without features of Down syndrome is described. The majority of bone marrow cells analysed belonged to a chromosomally abnormal clone with trisomy for chromosomes 18 and 21. Complex intrachromosomal rearrangements of one chromosome 21,...
Topics
- Chromosome Aberrations
- Chromosomes, Human, Pair 21
- Down Syndrome
- Female
- Follow-Up Studies
- Humans
- In Situ Hybridization, Fluorescence
- Infant, Newborn
- Leukopoiesis
- Myeloproliferative Disorders
- Phenotype