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Article

Transient abnormal myelopoiesis in neonates: GATA get the diagnosis.

Archives of pathology & laboratory medicine - 1 Oct 2014

Bombery Melissa, Vergilio Jo-Anne

Abstract excerpt

Transient abnormal myelopoiesis occurs exclusively in patients with Down syndrome (constitutional trisomy 21), manifests in the neonatal period, and is characterized by circulating megakaryoblasts with varied degrees of multisystem organ involvement. In most cases, this process resolves spontaneously by 3 to 6 months of age, but for some, the disease can be fatal. Affected patients are particularly prone to...

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Source

Identifiers

PMID: 25268193
DOI: 10.5858/arpa.2014-0304-CC

Genes

GATA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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