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Article

Transient leukemia with trisomy 21: Description of a case and review of the literature

25 Sept 1995

Abstract excerpt

Transient myeloproliferative disease (TMD) is often associated with a trisomy 21 cell line, but it is not always associated with clinical signs of Down syndrome. We report on a phenotypically normal newborn boy who presented with a high white blood cell count, undifferentiated blasts, and cutaneous leukemic infiltrates and compare this patient with the literature on TMD and trisomy 21. Chromosome analysis of bone...

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PMID: 8533839
DOI: 10.1002/ajmg.1320580404

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